Solution: It's All Greek To Me
Answer: VIN

Written by Amos Eshel and Jason Deakins

The puzzle consists of 18 cluetations accompanied with boxes of various sizes, and a pyramid of letters.
The first step is to unmangle the clues and then figure out the answer. Then, the answer should be mangled in the same manner as the clue to yield another word. Next the solver must recognize that each of the mangled answers contains a Greek letter’s name.

Mangled ClueTransformation DescriptionUnmangled ClueUnmangled AnswerMangled Answer
SWISSDAELYMOUNTAINROUTENESTwo interwoven clues.
The 2nd one has its ’I’s turned into ’E’s
Swiss Mountain/Daily RoutinesALP/HABITSALPHABETS
PLATINUMWCAISNWGOLDVYOUNGREVSILVERUBROTHREU+platinum/gold/silver/BRONZE
Swap last 2 letters of each word
Surround with wvuT
Cain’s younger brotherABELBRONZE TABLET
CHATTOOUCHUFEMTOSTCHONSTRUPICOCTCHDDITIONNANOALReplace 1st letter with CH
Add SI prefix sequentially before last 2 letters
You must construct additionalPYLONSCHYLOMICRONS
UNLFASTEORELMOVOSELPARATODILSCONNECOOOLCULOOFLOAdd L between 2nd & 3rd
Convert last letter to O
Unfasten, remove, separate, disconnect, or cut offDETACHDEL TACO
ADAGASCANIMAACHAROOHEOICE Drop 1st & last lettersMadagascar animal Sacha Baron Cohen voicedLEMUREMU
BRUSSIANITAISNCHORSERADISHISPTHUMMUSEYERNOLIVEOILTAC AESARTUALYLFREMOULADEENHCSwap last 2 letters
Replace 2nd letter with a dressing/dip starting with that letter
Britain’s chips they’re not actually FrenchFRIESFRANCHISE
ONMEIMALMEVOMEUSEMEDAMERTYMEQOMESTUMEMEAdd ME after 2nd letter.
Add ME after last letter.
1st letter += 12
Animal House party costumeTOGAHOME GAME
FERRCARTONELLFCASEILMBLCRATEANKPACKANDSCREAMBININGInsert a container synonym before the last three letters of the wordFerrell film blank and ScreamingKICKINGKICKBOXING
PSPEALMIMPORTCELPLEDLWLEPSPEANGRemove 3rd & 4th letters from the end
Copy the 2nd letter to the front of the word
special importance placed while speakingEMPHASISMEMPHIS
RAYERUNDINGUESPONSEUROMUHORUSUDrop 1st letter
Add U to end
Prayer ending response from chorusAMENMENU
MDESAECEDMROMDEYALEDReverse word
Add M to front
Delayed or deceasedLATEMETAL
RESRAUSIDENTRESEAUILRESFAUNALRESBAUSSPrecede each word with RES
Replace second letter of each with with AU
Resident Evil Final BossTYRANTRESTAURANT
TBALLOCOMECAYERLCAMRCOBOROUGHOCXSACHUSETTSACSDrop 1st letters.
Move (original) 2nd & 3rd letters to end.
Insert a C between above two.
Football Team Player From Foxborough MassachusettsPATRIOTRIOT ACT
SPPPLESPASEDSPLCOHOLICSPEVERAGEReplace the first letter of each word with SPApple Based Alcoholic BeverageCIDERSPIDER
THEANSPIRATIOTHEXOTHEKTEPHETHECINGTHEVERRAdd THE to start of word
First Letter Shift +18
Drop last letter
Inspiration for Stephen King’s DerryBANGORTHE TANGO
MICOFMFEEFANAFVYSOLOSRLAKIDLNEYAdd solfege note to start of word
Add first letter of note in center of word
Coffee, navy, or kidneyBEANTIBETAN
TOPSCAESARBOTTOMCHARMEDATSTRANGELast letter to front
Add quark pair to front & back
Caesar’s dateIDESUPSIDE DOWN
DEATHROCINANTEFAMINEORCONQUESTSECRETARIATPrecede each word with a horseman of the apocalypseRocinante or SecretariatHORSEWARHORSE

Collapsing the Greek letter’s name to a single character causes the mangled answer lengths to match the boxes that accompany each clue.

These boxes are the same lengths as the steps of the pyramid. Pulling the letter from the pyramid in the same position as the greek letter and then reading in Greek alphabet order yields an additional mangled clue, with enumeration provided by the blanks beneath the pyramid:

IIIRMNL XIXNGR XVIPL

This mangled clue can be unmangled to:
CRIMINAL SINGER APPLE (remove all vowels, replace first letter with Roman numeral equivalent)
The answer to the clue is FIONA, and mangling the answer in the same manner gives the puzzle answer VIN.